Ten Representative Publications
M. Scardigli, M. Pásek, L. Santini, C. Palandri, E. Conti, C. Crocini, M. Campione, L.M. Loew, A.A.F. de Vries, D. A. Pijnappels, F. S. Pavone, C. Poggesi, E. Cerbai, R. Coppini, P. Kohl, C. Ferrantini, L. Sacconi; Optogenetic confirmation of transverse-tubular membrane excitability in intact cardiac myocytes. J Physiol (2024).
V. Biasci, L. Santini, G.A. Marchal, S. Hussaini, C. Ferrantini, R. Coppini, L.M. Loew, S. Luther, M. Campione, C. Poggesi, F.S. Pavone, E. Cerbai, G. Bub, L. Sacconi; Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: dissecting the role of cardiac alternans in terminating rapid rhythms. Basic Res Cardiol. (2022).
E. A. Rog-Zielinska, M. Scardigli, R. Peyronnet, C. M. Zgierski-Johnston, J. Greiner, J. Madl, E. T. O'Toole, M. K. Morphew, A. Hoenger, L. Sacconi, P. Kohl; Beat-By-Beat Cardiomyocyte T-Tubule Deformation Drives Tubular Content Exchange. Circ Res. (2020).
M. Scardigli, C. Muellenbroich, E. Margoni, S. Cannazzaro, C. Crocini, C. Ferrantini, R. Coppini, .P Yan, L. M Loew, M. Campione, L. Bocchi, D. Giulietti, E. Cerbai, C. Poggesi, G. Bub, F. S. Pavone, and L. Sacconi; Real-time optical manipulation of cardiac conduction in intact hearts, J Physiol (2018).
M. Scardigli, C. Crocini, C. Ferrantini, T. Gabbrielli, L. Silvestri, R. Coppini, C. Tesi, E. A. Rog-Zielinska, P. Kohl, E. Cerbai, C. Poggesi, F. S. Pavone, L. Sacconi; Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy, Proc Natl Acad Sci U S A (2017).
C. Crocini, C. Ferrantini, R. Coppini, M. Scardigli, P. Yan, L. M. Loew, G. Smith, E. Cerbai, C. Poggesi, F. S. Pavone, L. Sacconi; Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation. Sci Rep. (2016).
C. Crocini, R. Coppini, C. Ferrantini, P. Yan, L. M. Loew, C. Tesi, E. Cerbai, C. Poggesi, F. S. Pavone, L. Sacconi; Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure. Proc Natl Acad Sci U S A (2014).
L. Sacconi, C. Ferrantini, J. Lotti, R. Coppini, P. Yan, L. M. Loew, C. Tesi, E. Cerbai, C. Poggesi, F. S. Pavone; Action potential propagation in transverse-axial tubular system is impaired in heart failure, Proc Natl Acad Sci U S A (2012).
V. Nucciotti*, C. Stringari*, L. Sacconi*, F. Vanzi*, L. Fusi, M. Linari, G. Piazzesi, V. Lombardi and F. S. Pavone; Probing myosin structural conformation in vivo by second-harmonic generation microscopy, Proc Natl Acad Sci U S A (2010).
(* Equally contributing authors)
L. Sacconi, D. A. Dombeck, and W. W. Webb; Overcoming photodamage in second-harmonic generation microscopy: Real-time optical recording of neuronal action potentials, Proc Natl Acad Sci U S A (2006).
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