OptoCARD is a joint research laboratory established by Institute of Clinical Physiology, National Research Council (IFC-CNR) in collaboration with the University of Florence - Department of NEUROFARBA.
Our mission is to develop cutting-edge optical technologies to advance the understanding of cardiac physiology across scales: from the nanoscale to the microscale and up to the mesoscale.
Our team is dedicated to developing advanced optical imaging methods that allow us to study the heart in unprecedented detail. By applying these innovative techniques, we investigate cardiac physiology in both healthy and diseased states, seeking to understand how the heart functions and adapts in different conditions.
Through this comprehensive approach, we aim to shed new light on the heart’s mechanisms, from molecular interactions all the way to the performance of the entire organ.
Building on these advances, our research is now entering a new phase through HeartCORE, an ERC Advanced Grant project designed to significantly expand the scope and translational impact of our work. HeartCORE integrates high-resolution three-dimensional functional and structural imaging of the whole heart with computational modelling to uncover how cardiac remodelling drives electrical dysfunction and arrhythmogenesis.
HeartCORE - Boosting predictive concepts on arrhythmogenesis resolving and unifying cardiac electrophysiology and structural remodelling at organ-level.
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